October 14, 2008: Green Fluorescent Protein (GFP), the protein that earned the 2008 Nobel Prize
for its discoverers, was a PDB Molecule of the Month in June 2003. Read more about exploring and improving GFP
on the PDB website.
August 13, 2008: increased crowding by surrounding macromolecules causes the protein to dramatically change shape and reveal a hidden site recognized by antibodies used in Lyme disease diagnostics. The paper
by Margaret S. Cheung, Pernilla Wittung-Stafshede and coworkers has been published in Proc. Natl. Acad. Sci. USA
, DOI: 10.1073/pnas.0803672105.
June 16, 2008: CAS scientists have discovered
that half of the known organic chemical substances can be described by just 143 molecular shapes.